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I checked from my side, and Opus is available in Microsoft Copilot Chat under the model selector (see the attached screenshot).
However, availability may vary depending on your tenant, license, region, and Microsoft's rollout schedule.
Also, Microsoft has documentation on selecting AI models for Copilot Studio agents, including preview and experimental models: https://learn.microsoft.com/en-us/microsoft-copilot-studio/authoring-select-agent-model
It explains the supported model selection experience, requirements, and current limitations.
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